Insulin Zinc Suspension Pharmacology
Insulin Zinc Suspension
Insulin stimulates glucose transport across cell membrane by ATP dependent translocation of glucose transporters GLUT1 and GLUT4 to the plasma membrane and by increasing their activity. Insulin promotes the expression of genes directing synthesis of glucose transporters. It also regulates genes for a large number of enzymes and carriers primarily through muscle action potential (MAP) kinases
Insulin causes increased production of glucokinase improves intracellular utilization of glucose. It also stimulates glycogen synthetase and enhances glycogen synthesis and inhibits phosphorylase and thus decreases glycogenolysis in liver. Insulin reduces synthesis of phosphoenol pyruvate carboxykinase and inhibits gluconeogenesis. It inhibits lipolysis in adipose tissue and favours triglyceride synthesis. Insulin increases clearance of VLDL and chylomicrons by stimulating transcription of vascular endothelial lipoprotein lipase. Insulin improves synthesis of proteins from amino acids and prevents breakdown of proteins.
Distribution: It is widely distributed throughout the body.
Metabolism: It is metabolized in liver, muscles, and kidney.
Peak action: 7-15 hrs.
2. Lipodystrophy at injection site
4. Insulin resistance
2. Along with other drugs
3. Along with alcohol
6. Hepatic impairment
7. Renal impairment
8. Rotate the injection site
9. In adrenal insufficiency
10. In pituitary insufficiency
2. Type II diabetes mellitus associated with chronic infections like tuberculosis
3. Pregnant diabetics
Drugs which increase hypoglycaemic effect of insulin : Alcohol, anabolic steroids, beta-blockers, clofibrate, guanethidine, MAO inhibitors, phenylbutazone, salicylates, tetracyclines.
S.C.: Adults and children: 0.5 to 1 U/kg/day. Adjust dosage based on blood glucose level.
Adolescents: 0.8 to 1.2 U/kg/day.
Home Delivery for Insulin Zinc Suspension in Your City
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Please be aware that you should take insulin zinc suspension only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for insulin zinc suspension before they complete the sale. You can get this information while placing the order for insulin zinc suspension with the pharmacy.
Insulin Zinc Suspension is a generic medicine name and there are several brands available for it. Some of the brands for insulin zinc suspension might be better known than insulin zinc suspension itself. If the pharmacy that's willing to deliver medicines to your home doesn't have insulin zinc suspension in stock, you can ask for one of the branded alternatives for insulin zinc suspension.