Ciprofloxacin (Eye/Ear Drops) Pharmacology

Ciprofloxacin (Eye/Ear Drops)

About Ciprofloxacin (Eye/Ear Drops)
Second generation fluoroquinolone antibiotic, Ophthalmic Antibiotic.
Mechanism of Action of Ciprofloxacin (Eye/Ear Drops)
Ciprofloxacin is a bacteriostatic at low concentration and bactericidal at high concentration. It act by inhibiting the enzyme DNA gyrase (Topoisomerase 2) and Topoisomerase 4.DNA gyrase helps in the formation of a highly condensed three dimensional structure of the DNA by its nicking and closing activity and also by introducing negative supercoil in to the DNA double helix. Ciprofloxacin inhibits DNA gyrase which results in abnormal linkage between opened DNA and gyrase and negative supercoiling is also impaired. This will inhibits transcription of DNA in to RNA and subsequent protein synthesis.
Pharmacokinets of Ciprofloxacin (Eye/Ear Drops)
Absorption: Absorption after topical application is minimal:
Onset of Action for Ciprofloxacin (Eye/Ear Drops)
N/A
Duration of Action for Ciprofloxacin (Eye/Ear Drops)
N/A
Half Life of Ciprofloxacin (Eye/Ear Drops)
N/A
Side Effects of Ciprofloxacin (Eye/Ear Drops)
Eye drops:
1.Burning
2.Irritation
3.Itching
4.Swelling
5.Redness
6.Pain in or around the eyes
Ear drops:
1.Hearing loss
2.Ringing in the ear
3.Dizziness
4.Loss of coordination
5.Stinging
6.Headache
7.Unpleasant sensation
8.Tingling
9.Rashes
10.Worsening ear pain

Contra-indications of Ciprofloxacin (Eye/Ear Drops)
1.Hypersensitivity to Ciprofloxacin
2.Perforations on the tympanic membrane (ear drops)
Special Precautions while taking Ciprofloxacin (Eye/Ear Drops)
1.Prolonged use
2.If irritation occurs then discontinue the use of medicaments
3.Avoid contact lenses
4.Wear sun glasses if sensitivity to sunlight occurs
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
NEONATES: contraindicated
Indications for Ciprofloxacin (Eye/Ear Drops)
1.Bacterial infections of the ears (external Otitis)
2.External ocular infections-conjunctivitis, corneal ulcers
Interactions for Ciprofloxacin (Eye/Ear Drops)
N/A
Typical Dosage for Ciprofloxacin (Eye/Ear Drops)
Ciprofloxacin 0.3 %w/v solution is available.
Eye drops: 2 or 3 drops should be instilled in the affected eye for 2-3times daily,
Eye ointment: Apply ? inch ribbon 6 - 8 times daily and then reduce the dose depending on infection, for trachoma: Apply 6 - 12 hourly for 1 - 2 months
Ears: The area should be cleaned and 3 drops instilled in the affected ear 2 times daily for 1 week.
Schedule of Ciprofloxacin (Eye/Ear Drops)
N/A
Storage Requirements for Ciprofloxacin (Eye/Ear Drops)
Store at cool dry place. Do not freeze. Keep out of the reach of children
Effects of Missed Dosage of Ciprofloxacin (Eye/Ear Drops)
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Ciprofloxacin (Eye/Ear Drops)
Give supportive measures and symptomatic treatment. The exposed eye should be irrigated with copious amounts of water for at least 15 minutes.

Home Delivery for Ciprofloxacin (Eye/Ear Drops) in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including ciprofloxacin (eye/ear drops).

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for ciprofloxacin (eye/ear drops) and other medicines and health products. Home delivery services for ciprofloxacin (eye/ear drops) may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take ciprofloxacin (eye/ear drops) only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for ciprofloxacin (eye/ear drops) before they complete the sale. You can get this information while placing the order for ciprofloxacin (eye/ear drops) with the pharmacy.

Ciprofloxacin (Eye/Ear Drops) is a generic medicine name and there are several brands available for it. Some of the brands for ciprofloxacin (eye/ear drops) might be better known than ciprofloxacin (eye/ear drops) itself. If the pharmacy that's willing to deliver medicines to your home doesn't have ciprofloxacin (eye/ear drops) in stock, you can ask for one of the branded alternatives for ciprofloxacin (eye/ear drops).