Distribution - Its distribution depending upon the route of administration, local anesthetics are distributed to some extent to all body tissues, with high concentrations found in highly perfused organs such as the liver, lungs, heart, and brain. 95% bound to the plasma proteins. Crosses the placental barrier
Metabolism - Metabolized in the liver via conjugation with glucuronic acid. The major metabolite of bupivacaine is 2, 6-pipecoloxylidine
Excretion - Excreted through urine
8.1 hours (neonates)
2. Cardiac arrhythmias.
3. Respiratory failure.
2. Digital block.
3. I.V. regional anaesthesia.
4. Para cervical block in obstetrics.
5. Spinal anaesthesia
2. Hepatic dysfunction.
4. Heart disease.
5. Debilitated patients.
2. Epidural anaesthesia.
3. Spinal anaesthesia.
4. Nerve block.
Lignocaine & Mepivacaine: Efficacy potentiated by bupivacaine.
INJ 15-30ml of 0.25% or 0.5%
INJ 10-20ml of 0.25% or 0.5%
Peripheral nerve block:
INJ 5ml of 0.25% or 0.5% (12.5-25mg)
2.5 mg/kg or 400mg daily
Sympathetic nerve block:
INJ 20-50ml of 0.25%
INJ 1-3.7 mg/kg
INJ 1.25 mg/kg/dose
Home Delivery for Bupivacaine in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including bupivacaine.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for bupivacaine and other medicines and health products. Home delivery services for bupivacaine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take bupivacaine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for bupivacaine before they complete the sale. You can get this information while placing the order for bupivacaine with the pharmacy.
Bupivacaine is a generic medicine name and there are several brands available for it. Some of the brands for bupivacaine might be better known than bupivacaine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have bupivacaine in stock, you can ask for one of the branded alternatives for bupivacaine.