Antiemetic action: Antiemetic activity is by blocking dopamine receptor (D2 receptor) in the Chemoreceptor trigger zone (CTZ)
Migraine: Prochlorperazine has been used in migraine to control severe nausea and vomiting unresponsive to Antiemetics and to relieve the pain of severe migraine attacks unresponsive to parenteral Dihydroergotamine or Sumatriptan.
Vertigo: Prochlorperazine are also used in vertigo to control associated vomiting.
2. Extrapyramidal reactions
7. Dry mouth
9. Blurred vision
10. Cholestatic jaundice
12. Haemolytic anaemia
16. Weight gain
4.Patient taking antidepressants
5.During pediatric surgery
2. Hepatic impairment
3. Cardiovascular disease
5. Parkinsons disease
8. Prostatic hyperplasia
9. Patient exposed to extreme heat
Below 2 years : Contraindicated
2. Treatment of vertigo
Aluminium salts: Decrease efficacy. Antacids should be given 1hour before or 2 hours after prochlorperazine.
Anticholinergics: Decrease efficacy and increase the anticholinergic side-effects of prochlorperazine.
Barbiturates: Decrease efficacy.
Barbiturate anaesthetics: Increase frequency and severity of neuromuscular excitation and hypotension.
Bromocriptine: Efficacy decreased by prochlorperazine.
Charcoal: Prevents absorption of prochlorperazine.
Lithium: Disoreintation, unconsciousness and extrapyramidal symptoms.
Meperidine: Excessive sedation and hypotension.
TCAs: Serum concentration increased by prochlorperazine.
Propranolol: Increased plasma levels of both drugs.
MAOIs: Additive orthostatic hypotensive effect.
Lab tests: Pregnancy tests: False positive results.
Plasma bound iodine (PBI): Increase in PBI occurs.
Psychoses, Nausea, Vomiting, Migraine and Vertigo15 - 30 mg / day in 3 divided doses
Anxiety: 15 - 20 mg / day in 3 or 4 divided doses
Children: 5 - 10 mg / day in 2 divided doses
Maximum daily dose: 20 mg / day
Home Delivery for Prochlorperazine in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including prochlorperazine.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for prochlorperazine and other medicines and health products. Home delivery services for prochlorperazine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take prochlorperazine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for prochlorperazine before they complete the sale. You can get this information while placing the order for prochlorperazine with the pharmacy.
Prochlorperazine is a generic medicine name and there are several brands available for it. Some of the brands for prochlorperazine might be better known than prochlorperazine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have prochlorperazine in stock, you can ask for one of the branded alternatives for prochlorperazine.