It is also useful in migraine prophylaxis. The monoamine uptake blocking property is related to migraine prophylactic activity. These are suited for patient with depression.
Distribution: It is widely distributed in the body in protein bound form.
Metabolism: Nortriptyline is metabolised in the liver.
Excretion: Drug is excreted mainly through urine and small amount is excreted through faeces also.
5. Difficulty in accommodation
6. Difficulty in micturition
14. Mild sedation
2. Myocardial infarction
3. Severe convulsions
2. Hepatic impairment
3. Cardiac arrhythmia
4. Myocardial infarction
6. Heart failure
8. Angle closure glaucoma
9. History of urine retention
13. Patient on MAOI therapy (Discontinue the MAO inhibitor at least 2 weeks before Nortriptyline is started)
14. Slowly withdraw the drug with caution
15. Patient should be cautioned against driving vehicle, operating machine and activities requiring mental alertness, judgment
2. Panic disorder
3. Nocturnal enuresis
4. Migraine prophylaxis
Barbiturates: Serum levels of nortriptyline decreased; additive respiratory depressant effect.
Clonidine: Hypertensive crisis.
Dicoumarol: Increase in anticoagulation effects.
Disulfiram: Acute organic brain syndrome.
Fluoxetine & Haloperidol: Potentiate action of nortriptyline.
Levodopa: Its bioavailability is reduced, hypertensive episodes.
MAOIs, Furazolidone: Seizures, sweating, coma, hyperexcitability, hyperthermia, tachycardia, mydriasis, confusion, DIC and death.
Oral Contraceptives and Phenothiazines: Increase plasma levels of nortriptyline.
Smoking: Increases metabolic bio-transformation.
Alcohol: Sedative effect of alcohol potentiated.
Maximum daily dose: 300 mg
Children (5 - 12 years): 25 mg/ day to be taken 1 hour before bed time.
Children above 12 years: 50 mg to be taken 1 hour before bed time.
Maximum dose: 5 mg / kg / day
If the drug taken only at night is missed then skip the missed dose.
Home Delivery for Nortriptyline in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including nortriptyline.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for nortriptyline and other medicines and health products. Home delivery services for nortriptyline may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take nortriptyline only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for nortriptyline before they complete the sale. You can get this information while placing the order for nortriptyline with the pharmacy.
Nortriptyline is a generic medicine name and there are several brands available for it. Some of the brands for nortriptyline might be better known than nortriptyline itself. If the pharmacy that's willing to deliver medicines to your home doesn't have nortriptyline in stock, you can ask for one of the branded alternatives for nortriptyline.