Anti-D Immune Globulin Pharmacology

Anti-D Immune Globulin

About Anti-D Immune Globulin
Anti Rhesus disease medicine, IgG type antibody.
Mechanism of Action of Anti-D Immune Globulin
Rh sensitization may occur in nonsensitized Rho(D) negative women following transplacental
hemorrhage resulting from spontaneous or induced abortions.1-2 The risk of sensitization is higher in
women undergoing induced abortions than in those aborting spontaneously.1-3
Anti-D Immune Globulin is used to prevent the formation of anti-Rho(D) antibody in Rho(D) negative
women who are exposed to the Rho(D) antigen at the time of spontaneous or induced abortion (up to 12weeks? gestation). Anti-D Immune Globulin suppresses the stimulation of active immunity by Rho(D)
positive fetal erythrocytes that may enter the maternal circulation at the time of termination of the
Pharmacokinets of Anti-D Immune Globulin
Distribution: Vd; 8.59 lit
Onset of Action for Anti-D Immune Globulin
Duration of Action for Anti-D Immune Globulin
Half Life of Anti-D Immune Globulin
24-28 days
Side Effects of Anti-D Immune Globulin
2.Fever (pyrexia)
3.Skin reactions such as rash and itch
4.A general feeling of being unwell (malaise)
5.Pain, soreness or bruising at the injection site
Contra-indications of Anti-D Immune Globulin
1.Individuals whose blood type is rhesus (RhD) positive
Special Precautions while taking Anti-D Immune Globulin
1.People who have antibodies against immunoglobulin A (IgA)
2.People who have had atypical reactions following receipt of a blood transfusion or blood products.
3.Do not administer IM for ITP.
4.Avoid live vaccines for 3 month.
5.IgA deficiency
Pregnancy Related Information
Not recommended, it should be administered only postabortion or postmiscarriage
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Not recommended
Indications for Anti-D Immune Globulin
1.It is recommended to prevent the isoimmunization of Rho(D) negative women at the time of spontaneous or induced abortion of up to 12 weeks? gestation provided the following criteria are met:
a)The mother must be Rho(D) negative and must not already be sensitized to the Rho(D) antigen.
b)The father is not known to be Rho(D) negative.
c)Gestation is not more than 12 weeks at termination.
2.Preventing rhesus negative individuals who have received a rhesus positive blood transfusion from forming antibodies against the blood.
Interactions for Anti-D Immune Globulin
1.People who have received anti-D immunoglobulin should not receive the measles, mumps and rubella (MMR) vaccine within the following three months, as the efficacy of this vaccine may be reduced if it is administered during this period.
2.If patient need to be given anti-D immunoglobulin within two to four weeks of receiving a live vaccine, such as yellow fever, rubella, BCG or oral polio, the anti-D immunoglobulin may reduce the efficacy of these vaccines.
Typical Dosage for Anti-D Immune Globulin
Asdirected by the physician
Schedule of Anti-D Immune Globulin
Storage Requirements for Anti-D Immune Globulin
Store at 2-8?C (36-46?F). Do not freeze.
Effects of Missed Dosage of Anti-D Immune Globulin
Effects of Overdose of Anti-D Immune Globulin
Patients who receive rho(d) immune globulin (human) for Rh-incompatible transfusion should be monitored by clinical and laboratory means due to the risk of a hemolytic reaction.

Home Delivery for Anti-D Immune Globulin in Your City

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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for anti-d immune globulin and other medicines and health products. Home delivery services for anti-d immune globulin may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take anti-d immune globulin only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for anti-d immune globulin before they complete the sale. You can get this information while placing the order for anti-d immune globulin with the pharmacy.

Anti-D Immune Globulin is a generic medicine name and there are several brands available for it. Some of the brands for anti-d immune globulin might be better known than anti-d immune globulin itself. If the pharmacy that's willing to deliver medicines to your home doesn't have anti-d immune globulin in stock, you can ask for one of the branded alternatives for anti-d immune globulin.