Quinine sulphate Pharmacology
Quinine has direct action on muscle fibres. This increases the refractory period of skeletal muscle and the distribution of calcium within the muscle fiber, thereby diminishing the response to tetanic stimulation. It also decreases the excitability of the motor end-plate region, reducing the responses to repetitive nerve stimulation and to acetylcholine.
4. Abdominal cramps
6. Blurred vision
2. G-6- PD deficiency
3. Optic neuritis
2. Renal impairment
4. Atrial fibrillation
5. Myasthenia gravis
6. Optic neuritis
2. Nocturnal muscle cramps
3. Babesia microti infections
Anticoagulants: May enhance the action of warfarin and other oral anticoagulants enhanced.
Digoxin: Increased serum concentrations of digoxin.
Mefloquine: Avoid concurrent use since ECG abnormalities or cardiac arrest may occur. Risk of convulsions also increased. Give mefloquine at least 12 hours after the last dose of quinine sulphate.
Neuromuscular blocking agents: Neuromuscular blockade enhanced resulting in respiratory problems.
Urinary alkalinizers (e.g. Acetazolamide and Sodium bicarbonate): Increased quinine blood levels leading to toxicity.
Lab tests: Elevated values of urinary 17- ketogenic steroids may occur with the Zimmerman method.
Nocturnal muscle cramps: 200 - 300 mg at bed time
Babesia microti infections: 650 mg 3 - 4 times daily for 1 week
Children: Malaria: 25 mg / kg body weight / day in 8 hours for 5 - 7 days
Babesia microti infections: 25 mg / kg body weight / day in 8 hours for 1 week
Home Delivery for Quinine sulphate in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including quinine sulphate.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for quinine sulphate and other medicines and health products. Home delivery services for quinine sulphate may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take quinine sulphate only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for quinine sulphate before they complete the sale. You can get this information while placing the order for quinine sulphate with the pharmacy.
Quinine sulphate is a generic medicine name and there are several brands available for it. Some of the brands for quinine sulphate might be better known than quinine sulphate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have quinine sulphate in stock, you can ask for one of the branded alternatives for quinine sulphate.