Sodium Bicarbonate Pharmacology
Sodium bicarbonate can neutralize or reduce acids in the blood, or urine. It is also used in emergency medical situations (heart attacks, serious kidney or lung problems) to correct the normal acid-base balance in the blood or as an aid in treating overdoses with certain types of medications.Intravenous sodium bicarbonate therapy increases plasma bicarbonate, buffers excess hydrogen ion concentration, raises blood pH and reverses the clinical manifestations of acidosis.
Sodium bicarbonate is used in a serious condition called metabolic acidosis. This is when the acidity of blood and tissues is abnormally high. It arises when the body`s normal acid balancing mechanisms fail, for example, in cardiac arrest or severe kidney disease. Sodium bicarbonate neutralises the excess acid.
Excretion: Less than 1% is excreted in urine.
6. Pain at the site of injection
7. Venous irritation
8. Chemical cellulites
10. Tissue necrosis at the site of infiltration confusion
11. Swelling of the feet and legs
2. Respiratory alkalosis
3. Patients losing chlorides by vomiting or from continuous suction
4. Patient on diuretics which produces hypochloremic alkalosis
5. Hypocalcaemia in which alkalosis may produce tetany
8. Heart failure
2. Edema with sodium retention
4. Cushing`s syndrome
6. Heart problems
8. Low blood levels of calcium or potassium
9. Ulcers in the esophagus
2. Severe diarrhoea
3. Urine alkalinization
a) increased - Chlorpropamide, lithium, methotrexate, salicylate, tetracycline.
b) decreased - Anorexients, quinidine, sympathomimetics.
Incompatibility : Avoid adding sodium bicarbonate to parenteral solution containing calcium, precipitation may result. Norepinephrine and dobutamine are incompatible.
In cardiac arrest: 200 - 300 mEq of a 7.5 - 8.4 % solution as rapidly as possible and in emergency inject 300 - 500 ml of 5% solution.
Metabolic acidosis: 90 - 180 mEq/L as IV during first hour and then adjust the dose depending on patients response.
Urinary alkalization: 0.325 - 2 g in 3- 4 times daily for patients above 60 years maximum dose is 8g and in patients below 60 years is 17 g.
Children: 1 - 10 mEq/kg / day
Children up to two years of age: 1 mEq / kg IV bolus of 4.2% solution and dose may be repeated every 10 minutes. Maximum daily dose: 8 mEq/ kg
Home Delivery for Sodium Bicarbonate in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including sodium bicarbonate.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for sodium bicarbonate and other medicines and health products. Home delivery services for sodium bicarbonate may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take sodium bicarbonate only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for sodium bicarbonate before they complete the sale. You can get this information while placing the order for sodium bicarbonate with the pharmacy.
Sodium Bicarbonate is a generic medicine name and there are several brands available for it. Some of the brands for sodium bicarbonate might be better known than sodium bicarbonate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have sodium bicarbonate in stock, you can ask for one of the branded alternatives for sodium bicarbonate.